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Autophagic lysosome reformation in health and disease.
Nanayakkara R, Gurung R, Rodgers SJ, Eramo MJ, Ramm G, Mitchell CA, McGrath MJ. Nanayakkara R, et al. Among authors: eramo mj. Autophagy. 2023 May;19(5):1378-1395. doi: 10.1080/15548627.2022.2128019. Epub 2022 Nov 21. Autophagy. 2023. PMID: 36409033 Free PMC article. Review.
INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer.
Rodgers SJ, Ooms LM, Oorschot VMJ, Schittenhelm RB, Nguyen EV, Hamila SA, Rynkiewicz N, Gurung R, Eramo MJ, Sriratana A, Fedele CG, Caramia F, Loi S, Kerr G, Abud HE, Ramm G, Papa A, Ellisdon AM, Daly RJ, McLean CA, Mitchell CA. Rodgers SJ, et al. Among authors: eramo mj. Nat Commun. 2021 May 25;12(1):3140. doi: 10.1038/s41467-021-23241-6. Nat Commun. 2021. PMID: 34035258 Free PMC article.
Defective lysosome reformation during autophagy causes skeletal muscle disease.
McGrath MJ, Eramo MJ, Gurung R, Sriratana A, Gehrig SM, Lynch GS, Lourdes SR, Koentgen F, Feeney SJ, Lazarou M, McLean CA, Mitchell CA. McGrath MJ, et al. Among authors: eramo mj. J Clin Invest. 2021 Jan 4;131(1):e135124. doi: 10.1172/JCI135124. J Clin Invest. 2021. PMID: 33119550 Free PMC article.
Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance.
Xirouchaki CE, Jia Y, McGrath MJ, Greatorex S, Tran M, Merry TL, Hong D, Eramo MJ, Broome SC, Woodhead JST, D'souza RF, Gallagher J, Salimova E, Huang C, Schittenhelm RB, Sadoshima J, Watt MJ, Mitchell CA, Tiganis T. Xirouchaki CE, et al. Among authors: eramo mj. Sci Adv. 2021 Dec 17;7(51):eabl4988. doi: 10.1126/sciadv.abl4988. Epub 2021 Dec 15. Sci Adv. 2021. PMID: 34910515 Free PMC article.